Alzheimer's Disease Research Center (ADRC)
Our investigations focus upon the normal and pathological action of the microtubule associated protein, tau, as well as mechanisms of neuronal plasticity and its impairment in neurodegeneration.
CBS - What is Alzheimer's Disease?
CNN - Reducing Risks of Alzheimer's Disease
CNN Documentary - Filling the Blank: Alzheimer's Disease
Part 1: Alzheimer's Disease: Fear and Hope
Part 2: Groundbreaking Alzheimer's Study
Part 3: Waiting and Worrying
Part 4: The Search for an Alzheimer's Cure
CNN - Genetic Information is Crucial to Alzheimer's Research and Treatment
Wall Street Journal - Music Triggering Memories in Dementia Patients
Cold Spring Harbor Laboratory DNA Learning CenterAlzheimer's Disease - Senile Plaques
Alzheimer's Disease - Neurofibrillary Tangles
Alzheimer's Disease - Tau Protein
Alzheimer's Disease - Biochemistry and Acetylcholine
Colombian Alzheimer's Study
May 25, 2012
A family in Columbia is the subject of a clinical trial that may prove the efficacy of a preventative Alzheimer's Disease treatment. Karyn Wood of ABC Australia spoke to Dr. Kosik about this research and asked him first how many people are in this afflicted family.
Clinical Trials for Alzheimer's Disease Preventative Drug to Begin Early 2013
May 21, 2012
After an announcement by federal officials approving clinical trials for the drug Crenezumab, researchers searching for a way to treat Alzheimer's Disease are gearing up for a rare study that will allow them to test a therapy for a genetically predestined disease before its onset.
Kosik's Book "The Alzheimer's Solution" Wins Will Solimene Award for Excellence in Medical Communication
May 4, 2012
UC Santa Barbara professor of neuroscience Kenneth S. Kosik's book, "The Alzheimer's Solution: How Today's Care is Failing Millions and How We Can Do Better," has been awarded the Will Solimene Award for Excellence in Medical Communication. The award is presented by the New England chapter of the American Medical Writers Association.
The Tau Consortium on CNBC
April 5, 2012
Richard Rainwater, the Texan billionaire credited with turning around Disney by installing Michael Eisner as CEO, was diagnosed with progressive supranuclear palsy (PSP) in March 2009. The neurodegenerative disease is similar to Alzheimer's in that clumps of tau protein form neurofibrillary tangles which inhibit brain and motor function. Eager to find a treatment, just two months later he assembled 15 dementia experts like Dr. Bruce Miller of UCSF and our own Dr. Kenneth S. Kosik for the first meeting of the Tau Consortium, which is discussed in this segment from CNBC. The Consortium aims to fast-track research not only for PSP, but Alzheimer's and other tauopathies.
Alzheimer's May Be Treatable by 2025
April 1, 2012
While setting a target date risks falsely raising expectations, the 2025 "deadline" may not be as unrealistic as it seems.
Alzheimer's Disease Symptoms Reversed in Mice
A cancer drug given to mice eliminates brain-damaging proteins, leading to improved cognition within days, but will it work in humans?
Feinstein Lab Discovers New Direction in Alzheimer's Research
June 6, 2011
In what they are calling a new direction in the study of Alzheimer's disease, UC Santa Barbara scientists have made an important finding about what happens to brain cells that are destroyed in Alzheimer's disease and related dementias. The results are published in the online version of The Journal of Biological Chemistry.
Finding a Way To Prevent Alzheimer's Disease
February 17, 2011
More than five million Americans are living with it and every 70 seconds, a new case is diagnosed. Now with no cure in sight, researchers are trying a preemptive strike against Alzheimer's. CNN's Dr. Sanjay Gupta, a CBS News contributor reports.
Alzheimer Cluster Sparks Dream of Cure
January 28, 2011
It's a cruel disease that strips away a person's identity until they can no longer remember their loved ones or feed themselves. But normally, Alzheimer's does not attack until old age. For some, though, it strikes early -- beginning its attack in their late 30's. Now, one cluster of Early-onset Alzheimer sufferers in the mountains of Colombia could offer hope to families around the world.
With Alzheimer's Patients Growing in Number, Congress Endorses a National Plan
December 15, 2010
Congress has voted unanimously to create, for the first time, a national plan to combat Alzheimer's disease with the same intensity as the attacks on AIDS and cancer. The bill, expected to be signed by President Obama, would establish a National Alzheimer's Project within the Department of Health and Human Services, to coordinate the country's approach to research, treatment and caregiving.
Baby Boomer's Brainiac
Adlai Stevenson once said, "What counts is not the years in your life, but life in your years." Dr. Kenneth S. Kosik codirector of the Neuroscience Research Institute at the University of California, Santa Barbara, and founder of Cognitive Fitness and Innovative Therapies (CFIT)'s trying to make sure that a generation of baby boomers doesn't have their last years ruined by Alzheimer's disease and other dementia-related illnesses.
Behavioral Approach Improves Life for Dementia Patients, Caregivers
September 3, 2010
As scientists scramble to find compounds that slow disease progression, dementia patients and their loved ones may simply crave a good night's sleep and the ability to make it through the day. Indeed, better quality of life is what many of these families seek most, and non-pharmacologic approaches, such as one reported in this weekís JAMA, may yet offer the best hope for finding peace amid mental decline.
June 1, 2010
In Yarumal, Colombia, tucked away on a steep street in this rough-hewn mountain town, an old woman found herself diapering her middle-age children.
Alzheimer's Forestalling the Darkness with New Approaches
May 26, 2010
Interventions before symptoms appear could be key to slowing or stopping the leading cause of dementia.
Alzheimer's Prevention Strategies Remain an Elusive Challenge
May 26, 2010
Numerous ideas circulate for using diet and exercise to waylay the leading cause of dementia, but the evidence to back solid biomedical recommendations is weak.
How to Outsmart Alzheimer's
March 30, 2010
Dr. Kosik's off-campus project, Cognitive Fitness and Innovative Therapies (Cottage Center for Brain Fitness as of 2012), is trying to keep people at risk for Alzheimer's intellectually and physically fit with quizzes and other cognitive challenges to see if onset of the disease can be delayed, perhaps indefinitely. The program, which is being advised by many famous names in Alzheimer's research and treatment, also promotes diet changes and maintaining a social life to try to slow cognitive decline and lower the risk for Alzheimer's.
UCSB Scientists Discover How the Brain Encodes Memories at a Cellular Level
December 23, 2009
Scientists at UC Santa Barbara have made a major discovery in how the brain encodes memories. The finding, published in the December 24 issue of the journal Neuron, could eventually lead to the development of new drugs to aid memory. The team of scientists is the first to uncover a central process in encoding memories that occurs at the level of the synapse, where neurons connect with each other.
Clear Your Head
January 9, 2009
Brain training is suddenly big business. But can you get smarter without geriatric video games or wildly expensive lab tests? As Matt Fitzgerald of Outside Magazine learned, yes.